Karyopharm Therapeutics, Inc. logo

KPTI Karyopharm Therapeutics, Inc.

Biotechnology NasdaqGS

$4.39 -0.22 (-5.01%)
update: 2025-07-06
Prev Close $4.61
Market Cap $57.93M
Day Range $4.39 - $4.83
Open $4.69
P/E Ratio
52W Change -60.12%
24H Volume 34.84K
Dividend Yield %
EPS -11.175
DAY WEEK PRICE LEVEL

Trading Signals (KPTI)

Overall Signal

SELL

Strong sellish signal based on multiple indicators.

Confidence: 64%
Updated: 2025-07-06

Key Price Levels

Support Levels

  • Strong Support $3.41
  • Medium Support $3.74
  • Weak Support $4.06

Resistance Levels

  • Weak Resistance $4.72
  • Medium Resistance $5.04
  • Strong Resistance $5.37

Stop Loss Suggestions

  • Conservative $4.65
  • Moderate $4.88
  • Aggressive $5.21

Analyst Ratings

Current Rating

Strong Buy 3
Buy 2
Hold 1
Sell 0
Strong Sell 0

Chart Analyst Ratings Loading

Last Month

Strong Buy 4
Buy 2
Hold 1
Sell 0
Strong Sell 0

2 Months Ago

Strong Buy 4
Buy 2
Hold 1
Sell 0
Strong Sell 0

3 Months Ago

Strong Buy
Buy
Hold
Sell
Strong Sell

Signal Indicator

Indicator Signal Strength Timeframe
Moving Averages SELL
Short & Medium Term
Oscillators SELL
Short Term
Trend Indicators BUY
Short & Medium Term
Volume Indicators SELL
Short & Medium Term
Support/Resistance NEUTRAL
Short Term
Data Source: Consolidated ratings from various investment bank analysts. Ratings may change over time.

Stock Price Prediction Price Target Probabilities (KPTI)

Quarterly Outlook :

Annual Outlook

Technical Analysis (KPTI)

Trend Identification

Momentum Measurement

RSI (2025-07-06)

Relative Strength Index

SELL
Current RSI(14) 45.77
Oversold Neutral Overbought

RSI (45.77) is in the bearish territory, but not yet oversold. This indicates downward momentum. Monitor for continuation or signs of strength.

OBV (2025-07-06)

On-Balance Volume

Rising
OBV Trend Upward
OBV vs Price Confirming

OBV (-3049981.00) is falling, indicating selling pressure and distribution. Price is falling and OBV is falling. This is bearish confirmation, indicating selling pressure supports the price decrease. Consider holding short positions or initiating new ones. Volume is supporting the trend.

Stochastic (2025-07-06)

Stochastic Oscillator

BUY
%K Line 36.59
%D Line 33.44

Stochastics (%K: 36.59, %D: 33.44) are in the neutral zone (between 20 and 80). A bullish crossover (%K above %D) is observed, potentially signaling an upward trend reversal or continuation. Stronger signal if this occurs below 50.

CCI (2025-07-06)

Commodity Channel Index

BUY
CCI(20) 99.45

CCI (99.45) is between 0 and +100. This indicates bullish momentum is present, but not yet extreme. A move above 0 from negative territory (bullish zero-line cross) can indicate a potential buy signal.

Volatility Measurement

ATR (2025-07-06)

Average True Range

0.36
ATR(14) 0.36
ATR % of Price ...%

Current ATR is 0.3600. ATR indicates average volatility. Market conditions are relatively stable.

Bollinger Bands (2025-07-06)

Volatility Bands

SELL
Upper Band 4.63
Middle Band (MA20) 4.41
Lower Band 4.2
Band Width 10%

Current price (4.39) is within the Bollinger Bands (4.20 - 4.63). This suggests the price is trading within its typical volatility range. Price is below the Middle Band (4.41), indicating short-term bearish bias.

Risk Management & Potential Reversals (KPTI)

SAR (2025-07-06)

Parabolic Stop and Reverse

BUY
Current SAR 4.13
Distance from Price 5.92%

SAR points below price indicate bullish trend. Current SAR at 4.13 is 5.92% from price. Consider SAR as a potential stop-loss level to protect gains in an uptrend.

Stochastic (2025-07-06)

Neutral

Approaching Overbought
Stochastic Position 36.6
Crossover Status Bullish

Stochastic is in neutral territory (36.6). No clear overbought/oversold signal. Current crossover status: Bullish.

RSI (2025-07-06)

Reversal Perspective

No Divergence
RSI Divergence None
Overbought/Oversold Neither

Current RSI level is in neutral territory. No RSI divergence detected. Current RSI level doesn't suggest imminent reversal.

Bollinger Bands (2025-07-06)

Reversal Perspective

Normal Volatility
Band Position Mid-Range
Band Squeeze None

Bands show normal bandwidth. Price is in the middle of bands with normal bandwidth. No indication of imminent volatility expansion or reversal.

Holder List Top 20 (KPTI)

Holder Name Holder Type Shares Pct. Held Date Reported
Vanguard Group Inc INSTITUTIONAL 510294 5.95% 2025-03-31
Adage Capital Partners GP L.L.C. INSTITUTIONAL 421322 4.92% 2025-03-31
Palo Alto Investors Lp INSTITUTIONAL 324032 3.78% 2025-03-31
Eversept Partners, LP INSTITUTIONAL 257154 3% 2025-03-31
Blackrock Inc. INSTITUTIONAL 242742 2.83% 2025-03-31
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund MUTUALFUND 228100 2.66% 2025-03-31
Citadel Advisors Llc INSTITUTIONAL 206909 2.41% 2025-03-31
JPMORGAN CHASE & CO INSTITUTIONAL 170790 1.99% 2025-03-31
Catalio Capital Management, LP INSTITUTIONAL 155622 1.82% 2025-03-31
T. Rowe Price Investment Management, Inc. INSTITUTIONAL 139646 1.63% 2025-03-31
Avidity Partners Management, LP INSTITUTIONAL 134566 1.57% 2025-03-31
VANGUARD EXPLORER FUND MUTUALFUND 133878 1.56% 2025-01-31
VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund MUTUALFUND 109532 1.28% 2025-03-31
T. Rowe Price Small-Cap Value Fund, Inc. MUTUALFUND 85896 1% 2025-03-31
-Price (T.Rowe) U.S. Small-Cap Value Equity Trust MUTUALFUND 50085 0.58% 2025-03-31
BlackRock Funds-BlackRock Advantage Small Cap Core Fund MUTUALFUND 46618 0.54% 2025-02-28
Fidelity Concord Street Trust-Fidelity Extended Market Index Fund MUTUALFUND 46059 0.54% 2025-04-30
Delaware Group Equity Funds IV-Macquarie Healthcare Fund MUTUALFUND 33333 0.39% 2025-03-31
VANGUARD VARIABLE INSURANCE FUNDS-Small Company Growth Portfolio MUTUALFUND 24247 0.28% 2025-03-31
iShares Trust-iShares Micro-Cap ETF MUTUALFUND 16672 0.19% 2025-04-30