PYXS Pyxis Oncology, Inc.
Biotechnology NasdaqGS
SELL PYXS is showing a Bearish technical setup (SELL, 85% confidence) — RSI 31.7, MACD below its signal line. Key support $1.51, resistance $1.77.
Based on end-of-day data, updated after each U.S. market close. Not investment advice.
Trading Signals (PYXS)
How these signals performed on PYXS
Historical occurrences of each signal on this stock since January 2024, and the forward return that followed. Small samples are shown as-is—a handful of events is not a track record.
| Signal | Horizon | Times | Win rate | Median |
|---|---|---|---|---|
| RSI oversold recovery | 5d | 10 | 20.0% | -3.06% |
| 10d | 9 | 33.3% | -6.72% | |
| 20d | 9 | 33.3% | -10.92% | |
| RSI overbought reversal | 5d | 12 | 66.7% | +3.05% |
| 10d | 12 | 66.7% | +6.70% | |
| 20d | 12 | 75.0% | +13.62% | |
| MACD golden cross | 5d | 21 | 52.4% | +3.66% |
| 10d | 21 | 52.4% | +0.27% | |
| 20d | 21 | 57.1% | +1.72% | |
| MACD death cross | 5d | 21 | 52.4% | +1.18% |
| 10d | 21 | 47.6% | 0.00% | |
| 20d | 20 | 50.0% | +0.29% | |
| MA20/MA60 golden cross | 5d | 6 | 66.7% | +3.53% |
| 10d | 6 | 33.3% | -2.49% | |
| 20d | 6 | 83.3% | +6.83% | |
| MA20/MA60 death cross | 5d | 7 | 71.4% | +3.60% |
| 10d | 6 | 66.7% | +13.60% | |
| 20d | 6 | 66.7% | +23.50% | |
| Combined bearish setup | 5d | 4 | 0.0% | -4.44% |
| 10d | 4 | 0.0% | -7.08% | |
| 20d | 3 | 0.0% | -10.25% |
Sample period from 2024-01-01 to the latest close. Returns are gross of transaction costs and do not account for liquidity. A small number of occurrences is not statistically meaningful. Full method and market-wide results: backtest.php. Not investment advice.
Overall Signal
SELL
Strong sellish signal based on multiple indicators.
Key Price Levels
Support Levels
- Strong Support $1.24
- Medium Support $1.38
- Weak Support $1.51
Resistance Levels
- Weak Resistance $1.77
- Medium Resistance $1.9
- Strong Resistance $2.04
Stop Loss Suggestions
- Conservative $2.31
- Moderate $1.84
- Aggressive $1.97
Analyst Ratings
Current Rating
Signal Indicator
| Indicator | Signal | Strength | Timeframe |
|---|---|---|---|
| Moving Averages | SELL |
|
Short & Medium Term |
| Oscillators | SELL |
|
Short Term |
| Trend Indicators | SELL |
|
Medium Term |
| Volume Indicators | SELL |
|
Short & Medium Term |
| Support/Resistance | NEUTRAL |
|
Short Term |
Price Outlook Price Target Probabilities (PYXS)
Quarterly Outlook :
2026-11-05
Bullish Scenario
from current 44.2%
Strong upward momentum and confirmed bullish trend, with potential for significant price appreciation. Indicators point to sustained buying pressure. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
2026-11-05
Base Scenario
from current -7.37%
Price is likely to continue its moderate trajectory, reflecting underlying market conditions and historical volatility. Indicators suggest a balanced outlook. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
2026-11-05
Bearish Scenario
from current -55.25%
Increased selling pressure and potential for a significant price correction or downtrend. Indicators suggest waning bullish momentum or strengthening bearish forces. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
Annual Outlook
2026-11-05
Bullish Scenario
from current 88.4%
Long-term bullish trend with strong fundamental catalysts and sustained institutional buying. Expect significant capital appreciation over the year. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
2026-11-05
Base Scenario
from current -14.73%
Steady long-term growth consistent with market and industry averages. Price expected to follow a typical growth trajectory. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
2026-11-05
Bearish Scenario
from current -110.5%
Long-term bearish trend with significant headwinds from economic factors, industry disruption, or company-specific issues. Expect notable price depreciation. ADX (22.74) indicates a developing or moderate trend. +DI > -DI suggests bullish directional bias. RSI (39.20) is in bearish territory, indicating downward momentum. MACD line (-0.06) is below Signal line (0.14) (bearish crossover), confirming downward momentum. Both lines are below zero, reinforcing bearish trend. Current Weekly ATR is 0.40, indicating the average weekly price range.
Technical Analysis (PYXS)
Trend Identification
EMA
Exponential Moving Average
Current price (1.64) is below both Short MA (2.19) and Long MA (2.74). This indicates strong bearish momentum. Short MA (2.19) is below Long MA (2.74), a bearish crossover ('Death Cross' if it's a significant period). This indicates a downward trend. MAs (2.19, 2.74, 2.49) show mixed alignment, suggesting market indecision or range-bound activity. Consider short positions. Use the MAs as dynamic resistance levels.
MACD
Moving Average Convergence Divergence
MACD line is below the Signal line (bearish crossover). This indicates downward momentum. Histogram (-0.0200) is negative and expanding, confirming bearish momentum. Both MACD and Signal lines are below the zero line, reinforcing bearish momentum (bearish territory). This is a strong sell signal. Consider short positions.
ADX
Average Directional Index
ADX (30.74) indicates a strong trend is present. -DI (37.67) is above +DI (16.92), suggesting a bearish directional bias. This combination points to a strong downward trend. Consider taking short positions, as the strong downward trend is confirmed.
Momentum Measurement
RSI (2026-11-05)
Relative Strength Index
RSI (31.65) is in the bearish territory, but not yet oversold. This indicates downward momentum. Monitor for continuation or signs of strength.
OBV (2026-11-05)
On-Balance Volume
OBV (-1436232.00) is falling, indicating selling pressure and distribution. Price is falling and OBV is falling. This is bearish confirmation, indicating selling pressure supports the price decrease. Consider holding short positions or initiating new ones. Volume is supporting the trend.
Stochastic (2026-11-05)
Stochastic Oscillator
Stochastics (%K: 24.08, %D: 47.68) are in the neutral zone (between 20 and 80). A bearish crossover (%K below %D) is observed. This indicates downward momentum. Be cautious if it's already in the oversold region.
CCI (2026-11-05)
Commodity Channel Index
CCI (-99.24) is between -100 and 0. This indicates bearish momentum is present, but not yet extreme. A move below 0 from positive territory (bearish zero-line cross) can indicate a potential sell signal.
Volatility Measurement
ATR (2026-11-05)
Average True Range
Current ATR is 0.2300. ATR indicates average volatility. Market conditions are relatively stable.
Bollinger Bands (2026-11-05)
Volatility Bands
Current price (1.64) is within the Bollinger Bands (1.00 - 3.39). This suggests the price is trading within its typical volatility range. Price is below the Middle Band (2.19), indicating short-term bearish bias. Bollinger Bands are wide. This indicates high volatility. Prices tend to revert to the mean after extended periods of high volatility.
Risk Management & Potential Reversals (PYXS)
SAR (2026-11-05)
Parabolic Stop and Reverse
SAR points above price indicate bearish trend. Current SAR at 2.31 is 40.85% from price. Consider SAR as a potential take-profit level or to confirm a downtrend.
Stochastic (2026-11-05)
Approaching Oversold
Stochastic is approaching oversold territory (24.1). No reversal signal yet. Monitor for potential bullish crossover (K above D) or entry into oversold (20-) followed by reversal. Current crossover status: Bearish.
RSI (2026-11-05)
Reversal Perspective
Current RSI level is in neutral territory. An RSI divergence has been detected, which often precedes a price reversal. Monitor closely.
Bollinger Bands (2026-11-05)
Reversal Perspective
Bollinger Bands are widening, indicating high volatility and potential strong trend continuation.Price is in the lower half of the bands, suggesting a bearish bias.No indication of imminent volatility expansion or reversal.
Holder List Top 20 (PYXS)
| Holder Name | Holder Type | Shares | Pct. Held | Date Reported |
|---|---|---|---|---|
| Pfizer Inc | INSTITUTIONAL | 7032770 | 11.42% | 2025-03-31 |
| Laurion Capital Management, LP | INSTITUTIONAL | 3625974 | 5.89% | 2025-03-31 |
| Blackrock Inc. | INSTITUTIONAL | 3271974 | 5.31% | 2025-03-31 |
| Millennium Management Llc | INSTITUTIONAL | 2485276 | 4.04% | 2025-03-31 |
| Vanguard Group Inc | INSTITUTIONAL | 2436728 | 3.96% | 2025-03-31 |
| VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund | MUTUALFUND | 1294689 | 2.1% | 2025-03-31 |
| iShares Trust-iShares Russell 2000 ETF | MUTUALFUND | 1170884 | 1.9% | 2025-04-30 |
| Geode Capital Management, LLC | INSTITUTIONAL | 1109098 | 1.8% | 2025-03-31 |
| Tang Capital Management, LLC | INSTITUTIONAL | 1100000 | 1.79% | 2025-03-31 |
| Palo Alto Investors Lp | INSTITUTIONAL | 1037421 | 1.68% | 2025-03-31 |
| State Street Corporation | INSTITUTIONAL | 932198 | 1.51% | 2025-03-31 |
| Aberdeen Group plc | INSTITUTIONAL | 913045 | 1.48% | 2025-03-31 |
| VANGUARD INDEX FUNDS-Vanguard Extended Market Index Fund | MUTUALFUND | 782884 | 1.27% | 2025-03-31 |
| abrdn Healthcare Investors | MUTUALFUND | 626637 | 1.02% | 2025-03-31 |
| Fidelity Salem Street Trust-Fidelity Small Cap Index Fund | MUTUALFUND | 486786 | 0.79% | 2025-02-28 |
| iShares Trust-iShares Russell 2000 Value ETF | MUTUALFUND | 481569 | 0.78% | 2025-04-30 |
| iShares Trust-iShares Biotechnology ETF | MUTUALFUND | 299020 | 0.49% | 2025-04-30 |
| abrdn Life Sciences Investors | MUTUALFUND | 286408 | 0.47% | 2025-03-31 |
| Fidelity Concord Street Trust-Fidelity Extended Market Index Fund | MUTUALFUND | 250505 | 0.41% | 2025-04-30 |
| VANGUARD SCOTTSDALE FUNDS-Vanguard Russell 2000 Index Fund | MUTUALFUND | 223299 | 0.36% | 2025-02-28 |